Search results for "Macrophage receptor with collagenous structure"

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Expression of host defense scavenger receptors in spondylarthropathy

2001

Objective Reactive arthritis (ReA) is postulated to be caused by a defective host defense against gram-negative bacteria. HLA–B27 could play a role in this process, but does not account for the many HLA–B27 negative patients. The objective of this study was to test the expression of 3 macrophage scavenger receptors (SRs) that are responsible for innate immunity against gram-negative bacteria: SR class A type I (SR-AI), SR-AII, and the macrophage receptor with collagenous structure (MARCO). We postulate that defects in such receptors might also contribute to the host risk factors that increase the predisposition to ReA and perhaps other subtypes of spondylarthropathy (SpA). Methods Periphera…

AdultCD36 AntigensMalemusculoskeletal diseasesCellular immunityAdolescentInflammatory arthritisImmunologyPeripheral blood mononuclear cellArthritis ReactiveImmune systemRheumatologyProhibitinsSynovial FluidmedicineImmunology and AllergySynovial fluidHumansPharmacology (medical)Spondylitis AnkylosingRNA MessengerScavenger receptorReceptors ImmunologicDNA PrimersReceptors LipoproteinReceptors Scavengerbusiness.industryReverse Transcriptase Polymerase Chain ReactionMacrophagesSynovial MembraneMembrane ProteinsScavenger Receptors Class AMiddle AgedScavenger Receptors Class Bmedicine.diseaseMacrophage receptor with collagenous structuremedicine.anatomical_structureImmunologySalmonella InfectionsLeukocytes MononuclearFemaleSynovial membranebusinessArthritis and rheumatism
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